SubtiBank SubtiBank
Version comparison:

2019-06-18 12:06:382025-05-12 15:00:50

description

GTP cyclohydrolase IB, replaces FolE under conditions of zinc starvation

GTP cyclohydrolase IB, required for the initial step of queuosine synthesis ([SW|tRNA modification]), replaces [[protein|FolE]] under conditions of zinc starvation

locus

BSU03340

BSU_03340

function

biosynthesis of folate

biosynthesis of folate and queuosine

outlinks

bsu

BSU03340

BSU_03340

The protein

Catalyzed reaction/ biological activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate (according to Swiss-Prot)

GTP + H2O --> 7,8-dihydroneopterin 3'-triphosphate + formate + H+ (according to UniProt)

The protein

Protein family

GTP cyclohydrolase IV family (according to Swiss-Prot)

GTP cyclohydrolase IV family (single member, according to UniProt)